IL-24 anticorps

N° du produit ABIN1107832

Cet anticorps Souris Monoclonal détecte spécifiquement IL-24 dans EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour IL-24 anticorps (ABIN1107832)

Antigène: IL-24 (IL24) (Interleukin 24 (IL24))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-24 est non-conjugé

Application: Enzyme Immunoassay (EIA)

Clone: B-C54

Détail du produit anti-IL-24 anticorps

Specificité: This Monoclonal antibody recognises both natural and recombinant Human IL-24 (Interleukin-24) also known as MDA-7 or TH2-specific cytokine FISP.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ion Exchange Chromatography

Immunogène: Recombinant Human IL-24. Myeloma X63/AG.8653 x Balb/c node cells.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS without carriers and preservatives

Agent conservateur: Without preservative

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur IL-24

Antigène: IL-24 (IL24) (Interleukin 24 (IL24))

Autre désignation: Interleukin-24 / IL24

Sujet: Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.Synonyms: IL-24, MDA7, Melanoma differentiation-associated gene 7 protein, ST16, Suppression of tumorigenicity 16 protein

ID gène: 11009

NCBI Accession: NP_001172085

UniProt: Q13007

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy